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ۼ : 24-11-06 00:40
þ˸: ˾ƾ 7 ߿
 ۾ : AD
ȸ : 5  
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þ˸: ˾ƾ 7 ߿


1. þ˸ 忡 õ ° ߱ ġϴ.

2003 þ˸(Ÿٶ) Ʊ׶ Ʈ ̾ ° õ 𿡽׶-5(PDE5) Ǿϴ.

PDE5 ȯ GMP(cGMP) ظ Ͽ ߱(ED) մϴ. cGMP Ȯ մϴ. , Ȱ ̿ϽŰ 帣 մϴ. ̴ ظü ŵϴ. ̰ ߱ ߿ ä ߱ ̷ Դϴ.

PDE5 þ˸ ڱ ߱⸦ Ű ʽϴ. ̴ cGMP ʱ ڱ ؼ ߻ϴ Ű ȭ ⿡ Ͽ ڽ ü ֱ Դϴ. 

2. þ˸ ׻ ƴմϴ

ٸ PDE5 þ˸ Ӹ ƴ϶ ü ٸ Ȱٿ Ĩϴ. ׷ þ˸ ϱ ǻ ϴ ߿մϴ.

߱ δ , Ű, ȣ ȣ ۿ뿡 ޶ Դϴ. ߱(ED) 索̳ 󵿸ƽ庴 ɰ ¿ ȣ ֽϴ.

̴ Ʈ Ҿ ¡ ְ, Ư ۿ ְ, ٹ߼ ȭ̳ Ų Ű ʱ ֽϴ. , ü, ڿ ɿ ĥ ֽϴ. ׷ ǻ ʱ 򰡰 ſ ߿մϴ. ǻ ü ˻縦 ǽϰ ޽ ã ˻縦 ǽ ֽϴ. κ Ϲ ɸ յ ϴ.

ǻ簡 þ˸ ٸ PDE5 ϴ ߱ ٸ ȿ ġ ɼ ֽϴ. ü ߱ ġ ǻ翡 ϰų ǰ Ŭ 湮Ͽ ʽÿ. 

3. þ˸ ۿ Ϲ ϰ ߵ ֽϴ.

þ˸ Ϲ ۿδ , ȫ, ڸ̳ ๰ ִµ, ̴ Ӹ ๰ ݿմϴ. ȭҷ ߻մϴ.

ٸ ۿδ þ˸ 12~24ð ߻ ĥ 㸮 ֽϴ. κ ٸ ۿ ð ϴ. ׷ 幰 4ð ̻ ӵǰ 뽺 ߱Ⱑ ߻ ֽϴ. ̷ ߻ϰų Ǵ ٸ ۿ ִ Ƿ ʽÿ. 

4. 꿰 þ˸ ȥϸ ֽϴ.

þ˸ Ʈα۸(Ʈθ /), ̼ҼҸ ƮƮ Ǵ ̼ҼҸ ƮƮ 꿰 Բ ؼ ˴ϴ.

꿰 ֺ Ȯ()ϸ 󵿸 ȯ ȯ ˴ϴ. þ˸ Ÿ ߱ ġ 꿰 ϸ û ġ ֽϴ. ƹ̳ ƿ ȯ ๰ þ˸ ȥϸ ̷ ȿ Ÿ ֽϴ.

ٸ , Ǵ , ȯ, ˾, Ǵ ȯ ִ þ˸ ƴ ֽϴ. þ˸ ˷ (ȸ α, , ȣ ) ϰų , , ޽ Ÿ ޾ƾ մϴ. 

5. þ˸ Ʊ׶ ֽϴ.

þ˸ ǵ(Ʊ׶) ̱ 忡 õ ٸ PDE5 ٸ(Ʈ, Ź), ƹٳ(ٵ) ѷ ֽϴ.

ٸ PDE-5 ޸ þ˸ Ϸ翡 , 뷮( ༺ 2.5-5mg/) ֽϴ. ̴ Ȱ Ͽ ڹ߼ Ű þ˸ 缺 (BPH) ġ ȿ ϴ. ׷ ED Ϸ ϴ ִ ɸ BPH Ϸ 2~4ְ ɸ ֽϴ.

þ˸ ٸ ֿ 뷮 ӵǴ ð̸  쿡 ִ 36ð ֽϴ. ̰ ٷ "ָ "̶ ٴ Դϴ.

Ʊ׶ ȿ 4ð, Ʈ 5ð, ٵ ȿ 6ð ӵ˴ϴ. ̴ ؾ ϴ ٸ ߱ ࿡ ڹ߼ ϱ þ˸ ֿ Ǹ Ʈ Ǿϴ. 

6. Tadalafil Adcirca ̿ մϴ.

þ˸ ߱ 缺 (BPH) ġθ 㰡Ǿϴ. ׷ 󵿸ư(PAH) ġῡ Ǵ Adcirca(Ϲݸ Alyq) ٸ 귣 Ÿٶ ֽϴ.

PAH ϴ ߻ϴ Ư¡ ϴ ȯԴϴ. ̷ ϱ ϰ ǰ ᱹ ɺ ̾ ˴ϴ.

Adcirca Ǵ Alyq ϴ þ˸ ʽÿ. 

7. þ˸: Ϲ þ˸ Ƿ .

þ˸ Ϲ Ÿٶʷ ˴ϴ.

⼺ ¶ ౹ ε ƴ ڻ Ϲ þ˸ Ƿ ϼ. ˾ ȿ ִ, 뷮 󸶳 Ǵ ִ ϴ. ߻ϸ ٽ ƿ ϴ.

¶ ϴ , FDA Ǿǰ Ǹϴ ŷ 縦 ¶ Ʈ ϼ.